Learn how to prepare a mixed dose of insulin.
Questions About Mixing Humalog with Other Insulins
- Can Humalog and a longer-acting insulin (suspension insulin) be mixed in the same syringe and stored in the syringe until ready for use at a later time?
- Can Humalog be mixed with insulin produced by other manufacturers?
- Can Humalog be mixed with Humulin R?
- Can Humalog and Humulin N be mixed?
Can Humalog and a longer-acting insulin (suspension insulin) be mixed in the same syringe and stored in the syringe until ready for use at a later time?
Eli Lilly and Company has only studied the mixture of Humalog and Humulin N in prefilled syringes. That study showed that prefilled syringes of Humalog mixed with Humulin N were stable for 14 days at refrigerated conditions. It is recommended that prefilled syringes of Humalog mixed with Humulin N be stored in the refrigerator and used as quickly as possible. Syringes stored beyond 14 days should not be used. You should discuss the use of prefilled syringes with your healthcare provider.
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Can Humalog be mixed with insulin produced by other manufacturers?
The effects of mixing Humalog with insulin produced by other manufacturers have not been studied, and therefore cannot be recommended.
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Can Humalog be mixed with Humulin R?
The effects of mixing Humalog with Humulin R insulin have not been studied, and therefore cannot be recommended.
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Can Humalog and Humulin N be mixed?
Humalog should only be mixed with Humulin N on the advice of your doctor. Humalog and Humulin N can be mixed; however, Humalog should be drawn into the syringe first to prevent clouding of the Humalog vial insulin. The mixed insulin at this point should look uniformly cloudy in the syringe. Inject immediately after mixing.
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Humalog, Humalog Mix75/25, and Humalog Mix50/50 are available by prescription only. See Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Information for important facts about these products.
Important Safety Information
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are for use in patients with diabetes to control high blood sugar. Humalog should be used with a longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.
Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no clinical studies of the use of Humalog insulins in pregnancy or nursing mothers.
Potential side effects associated with the use of all insulins include low blood sugar, weight gain, low blood potassium, changes in fat tissue at the site of injection, and allergic reactions, both general and local. Humalog Mix75/25 and Humalog Mix50/50 should not be mixed with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.
Humalog insulins are available by prescription only. See the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Product Information for important facts about these products.
Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are for use in patients with diabetes to control high blood sugar. Humalog should be used with a longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.
Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no clinical studies of the use of Humalog insulins in pregnancy or nursing mothers.
Potential side effects associated with the use of all insulins include low blood sugar, weight gain, low blood potassium, changes in fat tissue at the site of injection, and allergic reactions, both general and local. Humalog Mix75/25 and Humalog Mix50/50 should not be mixed with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.
Humalog insulins are available by prescription only. See the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Product Information for important facts about these products.
Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.
