Side Effects
As with any medication, there are possible side effects associated with taking mixture insulin such as Humalog Mix75/25 and Humalog Mix50/50. The most common side effects experienced are:
Low blood sugar (hypoglycemia)
Low blood sugar symptoms can happen suddenly. Symptoms of low blood sugar may be different for each person and may change from time to time. Severe low blood sugar can cause seizures and death. Low blood sugar may affect your ability to drive a car or use mechanical equipment, risking injury to yourself or others. Know your symptoms of low blood sugar. Low blood sugar can be treated by drinking juice or regular soda or eating glucose tablets, sugar, or hard candy. Follow your healthcare provider's instructions for treating low blood sugar. Talk to your healthcare provider if low blood sugar is a problem for you.
For information on the causes and symptoms of hypoglycemia, as well as guidance on treating hypoglycemia, see low blood sugar.
Serious allergic reactions
Severe, life-threatening allergic reactions can happen with insulin. Get medical help right away if you develop a rash over your whole body, have trouble breathing, or suffer wheezing, a fast heartbeat, or sweating.
Reactions at the injection site
You may get redness, swelling, and itching at the injection site. If you keep having injection site reactions or they are serious, you need to call your healthcare provider. Do not inject insulin into a skin area that is red, swollen, or itchy.
Skin thickens or pits at the injection site (lipodystrophy)
This can happen if you don't change (rotate) your injection sites enough.
These are not all the side effects from Humalog Mix75/25 and Humalog Mix50/50. Ask your healthcare provider or pharmacist for more information.









